Fund Translational Science: To fund science projects which are translational, i.e. which have direct implications for the progress of country, through a competitive process in an open and transparent manner.

Problem-First Approach: Basic thrust would be to take stock of an existing problem and work backwards towards conducting research for a solution.

Interdisciplinary Synergy: Promoting an inter-disciplinary & translational approach in research for synergy, de-duplication and greater comprehensiveness & relevance of research activities.

National Priorities: Orient science towards addressing needs & issues of the country in key sectors like health, agriculture, energy, environment, security etc.

International Benchmarks: Attain demonstrable international benchmarks in scientific research.